Click on the column heading to arrange the table in ascending order (or descending order on a second click) of the column heading. A click on the # column or company column will return the order to the original order. The table is currently numbered according to alphabeitcal order of the companies. For other compilations, please visit the sites at the bottom of the table (especially # 10). For many other sites (primaily chemistry related) as well as pre-show Powerpoint and Trivia presentations, please visit http://murov.info. Sites developed and uploaded by Steven Murov, Professor Emeritus of Chemistry, Modesto Junior College http://murov.info/resume.htm .
# |
Drug |
Company |
function |
Test Stage, clinical trial links |
Sample Reference links |
Notes |
|
|||
---|---|---|---|---|---|---|---|---|---|---|
1 |
Kaletra | Abbvie | Phase 3 lop | lopi | HIV | |||||
2 |
Favipiravir | AdooQ Bioscience | treatment | Phase 3 favip | favipi | anitviral | ||||
3 |
nitric oxide | Air Liquide | treatment | Phase 2 | no | |||||
4 |
AT-100 (rhSP-D) | Airway Therapeutics | treatment | AT-1 | ||||||
5 |
AJ Vaccines | vaccine | aj | |||||||
6 |
NP-120 (Ifenprodil) | Algernon Pharm. | treatment | np | ||||||
7 |
AdCOVID | Altimmune | vaccine | adc | nasal spray | |||||
8 |
APN01 | APEIRON Biologics | treatment | Phase 1 | apn | |||||
9 |
LUNAR-COV19 | Arcturus Therapeutics | vaccine | Preclinical | Arc. | engineered RNA | ||||
10 |
danoprevir, ritonavir | Ascletis Pharma | treatment | Phase 1 da | dan. med | HIV, hepatitis C | ||||
11 |
Ciclesonide | AstraZeneca | treatment | Phase 2 cicle | cicles | asthma care | ||||
12 |
BPI-002 | BeyondSpring | treatment | bp | ||||||
13 |
Galidesivir (BCX4430) | Biocryst | treatment | gal | bcx | |||||
14 |
BNT162 |
BioNTech, Pfizer, CureVac |
vaccine | Preclinical | Bio | RNA based | ||||
15 |
BXT-25 | BIOXYTRAN | treatment | bxt | ||||||
16 |
CM4620-IE | CalciMedica Inc. | treatment | Phase 2 | cm4 | |||||
17 |
Ad5-nCoV | CanSino Biologics | vaccine | Phase 1 ad | CSB | modified virus | ||||
18 |
CEL-SCI | treatment | cel | immunotherapy | ||||||
19 |
Lopinavir, Ritonavir (LOPIMUNE) |
Cipla | Phase 3 lop | sci | HIV | |||||
20 |
S-Trimer | Clover Biopharm. | vaccine (subunit) | s-t | ||||||
21 |
Codagenix | vaccine | cod | |||||||
22 |
leronlimab (PRO 140) | CytoDyn | treatment | Phase 2, ler | ler | respiratory | ||||
23 |
baricitinib |
Eli Lilly |
treatment |
respiratory |
||||||
24 |
Emergent BioSolutions | treatment | eme | |||||||
25 |
EIDD-2801 | Emory Univ. Bio | treatment | cen dru | antiviral | |||||
26 |
Fusogenix | Entos Pharm. | vaccine | fus | DNA based | |||||
27 |
Generex | vaccine | gene | peptide vaccines | ||||||
28 |
remdesivir | Gilead | treatment | Phase 3 re | rem. sci cen | Ebola antiviral | ||||
29 |
gp96 | Heat Biologics | vaccine | hb, gp | ||||||
30 |
TJM2 | I-Mab Biopharma | treatment | tj | cytokine storm | |||||
31 |
TJ003234 | I-Mab Biopharma | treatment | Phase 1,2 tj | ||||||
32 |
ImmunoPrecise Antibodies | vaccine | imm |
PolyTope mAb Therapy |
||||||
33 |
Brilacidin | Innovation Pharm. | treatment | bri | developed for oral issues | |||||
34 |
INO-4800 |
Inovio Pharm. |
vaccine |
DNA based |
||||||
35 |
Integral Molecular | vaccine | im | |||||||
36 |
Prezista | J&J | treatment | |||||||
37 |
darunavir/cobicistat (PREZCOBIX) |
Janssen Pharm. | Phase 3 pre | prez | HIV | |||||
38 |
AmnioBoost | Lattice Biologics | treatment | phase 1 | amn | stem cell technology | ||||
39 |
LineaRx, Takis Biotech |
vaccine | lin | DNA based | ||||||
40 |
OT-101 | Mateon Therapeutics | treatment | phase 3 | ma | |||||
41 |
Medicago | vaccine | me1 | plant based | ||||||
42 |
IBV | MIGAL Research Inst. | vaccine | ibv | ||||||
43 |
mRNA-1273 | Moderna | vaccine | Phase 1 mr | mRNA mod | |||||
44 |
hydroxychloroquine | Mylan | treatment | clinical hyd | hy | malaria approved | ||||
45 |
NanoViricide | treatment | nan | nanotech | ||||||
46 |
Ruxolitinib | Novartis | treatment | Phase 2 rux | ruxo |
respiratory complications |
||||
47 |
NVX-CoV2373 | Novavax | vaccine | Phase 1 | nvx | MERS vaccine | ||||
48 |
ChAdOx1 nCoV-19 | Oxford | vaccine | Phase 1, ch | cha | adenovirus vaccine vector | ||||
49 |
OYA1 | OyaGen | treatment | oya | ||||||
50 |
Azithromycin | Pfizer | treatment | Phase 3 | azith | |||||
51 |
Tranexamic acid Cyklokapron |
Pfizer LGM Pharma |
treatment | Phase 1, 2 tran | tran | blod clotting | ||||
52 |
Predictive Oncology | vaccine | pre | AI Platform | ||||||
53 |
REGN3048, REGN3051 |
Regeneron Pharm. | treatment | Preclinical re | Reg. | virus mimic | ||||
54 |
Kevzara (Sarilumab) |
Regeneron, Sanofi | treatment |
Phase 2,3,
kev |
ke | arthritiis approved | ||||
55 |
actemra |
Roche | treatment |
Phase 3 act |
roc | arthritis appoved | ||||
56 |
Tocilizumab | Roche | treatment | Phase 2 tocil | tociliz | |||||
57 |
Gimsilumab | Roivant Sciences | treatment | gim | antibody | |||||
58 |
Nitazoxanide (Alinia) |
ROMARK | Phase 4 | nita | antiviral | |||||
59 |
Sanofi |
vaccine |
Preclinical |
RNA modification |
||||||
60 |
Losartan | Sharp Health Care | treatment | Preclinical losa | respiratory failure | |||||
61 |
Emapalumab, Anakinra | Sobi | treatment | Phase 2, 3 ema | emap |
respiratory complications |
||||
62 |
SNG001 | Synairgen Research | treatment | sn | syn | inhaler | ||||
63 |
|
Takeda | treatment | Preclinical | Tak | blood plasma | ||||
64 |
TZLS-501 | Tiziana Life Sciences | treatment | tzl | ||||||
65 |
Angiotensin 1-7 | Tocris Bio. | treatment | Phase 2, 3 angio | a17 |
respiratory complications |
||||
66 |
TNX-1800 | Tonix Pharm. | vaccine | tnx | ||||||
67 |
Favilavir | Toyama Chemical | treatment | fav | approved in China for C-19 | |||||
68 |
cGMP | Vaxart | vaccine | cgmp | ||||||
69 |
VIR-7831, VIR-7832 | Vir Biotechnology | treatment | Preclinical | Vir | antibodies | ||||
70 |
Zydus Cadila | vaccine | zyd | |||||||
71 |
chloroquine |
Zydus Cadila, Ipca Labs |
treatment | clinical chl | sci | malaria, arthritis approved | ||||
72 |
AM580 |
treatment | am580 | antiviral | ||||||
73 |
ribavirin | |||||||||
74 |
Vitamin D | treatment | test | vd | ||||||
75 |
Vitamin C (ascorbic acid) |
treatment | test | vitc | ||||||
76 |
||||||||||
77 |
||||||||||
78 |
||||||||||
79 |
||||||||||
80 |
||||||||||
The compilation above was extracted primarily from the web sites 2,3,5 below. For up-to-date information on the status of testing of any drug, please see reference 1. During the development of this site, other sites that have complimentary and supplementary information were found (see especially references 9, 10) but it was decided to go ahead and finish this site. The developer of this site does have a chemistry background, he is not a medical doctor, pharacologist or biochemist and has no expertise in the field of disease treatment or prevention. Any information obtained from this site should be checked and double checked by doing appropriate literature and Internet research on the topic. The links provided for each drug represent a very small sample of available Internet sites with information on the drug. The site is intended only as a quick reference and perhaps as a consideration of possible drugs for compassionate use. Please send comments and suggestions to murovs@yosemite.edu .
1. https://www.clinicaltrials.gov/ct2/results?cond=COVID-19
2. https://www.clinicaltrialsarena.com/analysis/coronavirus-mers-cov-drugs/
5. https://www.marketwatch.com/story/these-nine-companies-are-working-on-coronavirus-treatments-or-vaccines-heres-where-things-stand-2020-03-06 look for most current version
6
9.
https://www.bioworld.com/COVID19products
10.
a.
https://milkeninstitute.org/sites/default/files/2020-04/Covid19%20Tracker%20NEW4-17-20-3.pdf
b.
https://milkeninstitute.org/sites/default/files/2020-04/Covid19%20Tracker-4-1-WEB.pdf
11.
13.
https://www.clinicaltrials.gov/ct2/results?pg=1&load=cart&id=NCT04333550+OR+NCT04336904+OR+NCT04324489+OR+NCT04333420+OR+NCT04324996+OR+NCT04340232+OR+NCT04317092+OR+NCT04330586+OR+NCT04315298+OR+NCT04304313+OR+NCT04340544+OR+NCT04341675+OR+NCT04333628+OR+NCT04307693+OR+NCT04323631+OR+NCT04337216+OR+NCT04292899+OR+NCT04331470+OR+NCT04320615+OR+NCT04305106+OR+NCT04308317+OR+NCT04342221+OR+NCT04332107+OR+NCT04334044+OR+NCT04332913+OR+NCT04286503+OR+NCT04333472+OR+NCT04331665+OR+NCT04328272+OR+NCT04335071+OR+NCT04323514+OR+NCT04338698+OR+NCT04310228+OR+NCT04335552+OR+NCT04324021+OR+NCT04334967+OR+NCT04275414+OR+NCT04321174+OR+NCT04293887+OR+NCT04327388+OR+NCT04325893+OR+NCT04337918+OR+NCT04291729+OR+NCT04288713+OR+NCT04306393+OR+NCT04322123+OR+NCT04264533+OR+NCT04315480